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TNT Repository

Here you can find TNT estimates for a range of guideline recommendations. This repository will be updated with more TNT estimates shortly.

Have you done – or would like to do – TNT estimates that you would like us to publish here? Contact us!

Please note that for some of these estimates, all the information needed to perform the TNT estimates has not been available in the guidelines, and the estimates are therefore based on assumptions – which means that the estimates are rough, and the exact estimates should be interpreted with caution.

For details on how the estimates were done – click the links below each estimate. We do not take responsibility for the accuracy of the estimates that are performed by others.

A

Actinic keratosis

Swedish regional guideline on treating actinic keratoses

Link to estimates here. Performed by Minna Johansson and Victor Montori.

Time Needed to Treat (TNT)To implement the recommendation for all eligible
Time needed to improve the outcome for one more personNot possible to estimate due to no evidence of benefit
Time needed to provide the intervention for all eligible60 h for a GP in a practice of 2000 people per year
Time needed as proportion of time available5% of GPs total face-to-face time with patients (for all causes)

B

C

D

Diabetes

NICE guideline on treating type 2 diabetes

Link to estimates here. Performed by Minna Johansson and Victor Montori.

Time Needed to Treat (TNT)To implement the recommendation for all eligible
Time needed to improve the outcome for one more personNot estimated
Time needed to provide the intervention for all eligible45 h for a GP and 180 h for a nurse in a practice of 2000 people per year
Time needed as proportion of time available4% of GPs total face-to-face time with patients, and 16% of nurses’ total face-to-face time with patients (for all causes)

NICE guideline on prevention of type 2 diabetes

Link to estimates here. Performed by Minna Johansson and Victor Montori.

Time Needed to Treat (TNT)To implement the recommendation for all eligible
Time needed to improve the outcome for one more person47 h of GP time, 105 h of nurse time, and 86 h for professionals outside of GP practices, for one fewer person to progress from HbA1c 42-47 mmol/mol to > 48 mmol/mol in 5 years
Time needed to provide the intervention for all eligible103 h for a GP and 230 h for a nurse in a practice of 2000 people per year (and 190 h for professionals outside of the GP practice)
Time needed as proportion of time available9% of GPs total face-to-face time with patients, and 20% of nurses’ total face-to-face time with patients (for all causes)

P

Physical activity

NICE guideline on physical activity: brief advice for adults in primary care

Estimates in this BMJ publication. Performed by Minna Johansson and Victor Montori.

Time Needed to Treat (TNT)To implement the recommendation for all eligible
Time needed to improve the outcome for one more person3 h for GPs to increase self-reported physical activity for 1 adult
Time needed to provide the intervention for all eligible167 h in a GP practice of 2000 adults per year
Time needed as proportion of time available15% of GPs total face-to-face time with patients (for all causes)

S

Stroke

NICE guideline on multidisciplinary rehabilitation in stroke units

Link to estimates here. Performed by Minna Johansson and Victor Montori.

Time Needed to Treat (TNT)To implement the recommendation for all eligible
Time needed to improve the outcome for one more person101 h for one fewer person to have died 10 y after stroke (time split between nurses, physiotherapists, occupational therapists, and speech and language therapists)
Time needed to provide the intervention for all eligible1 400 000 h for all eligible in the UK population
Time needed as proportion of time available0.09% of nurses, 1.4% of physiotherapists, 0.9% of occupational therapists, and 2.7% of speech and language therapists total face-to-face time with patients (for all causes)

T

Trigger finger

UK guideline on corticosteroid injection for trigger finger

Link to estimates here. Performed by Minna Johansson and Victor Montori.

Time Needed to Treat (TNT)To implement the recommendation for all eligible
Time needed to improve the outcome for one more person0.5 h of GP time for one more person to avoid surgery
Time needed to provide the intervention for all eligible0.1 h in a GP practice of 2000 people per year
Time needed as proportion of time available0.009% of GPs total face-to-face time with patients (for all causes)


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